Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26066067 | 0.92 | KCNH2 (0.43) | KCNH2TPSAB1CA2 | |
| SCHEMBL26065616 | 0.87 | KMT2A (0.37) | KCNH2TPSAB1KDM2BKMT2AMEN1 | |
| SCHEMBL25368937 | 0.87 | KCNH2 (0.35) | KCNH2MEN1 | |
| SCHEMBL26065891 | 0.85 | TRPV4 (0.41) | KCNH2TPSAB1KDM2BKMT2AMEN1 | |
| SCHEMBL26065762 | 0.81 | EBP (0.39) | KCNH2TPSAB1KDM2BKMT2AMEN1 | |
| SCHEMBL26065919 | 0.81 | EBP (0.39) | KCNH2TPSAB1KDM2BKMT2AMEN1 | |
| SCHEMBL26065920 | 0.81 | EBP (0.39) | KCNH2TPSAB1KDM2BKMT2AMEN1 | |
| SCHEMBL26066093 | 0.80 | MEN1 (0.41) | KMT2AMEN1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL25371219 | 0.79 | PSEN1 (0.37) | KCNH2CA2 | |
| SCHEMBL26065774 | 0.79 | TLR7 (0.42) | KCNH2TPSAB1KDM2BHTR1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |