Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26065535 | 0.88 | MEN1 (0.42) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL25368228 | 0.87 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26064898 | 0.87 | MEN1 (0.43) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26066093 | 0.86 | MEN1 (0.41) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26066126 | 0.84 | MEN1 (0.39) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26066128 | 0.84 | MEN1 (0.41) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL26065512 | 0.82 | DDR1 (0.40) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26065806 | 0.81 | MEN1 (0.39) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26065408 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1MAPK1KDM4E | |
| SCHEMBL26065451 | 0.80 | KMT2A (0.46) | ALDH1A1KMT2AMEN1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |