⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327402 | 0.89 | TYMP (0.30) | — | |
| SCHEMBL22327400 | 0.89 | TYMP (0.30) | — | |
| SCHEMBL25754037 | 0.89 | TYMP (0.30) | — | |
| SCHEMBL22327445 | 0.88 | METTL3 (0.30) | — | |
| SCHEMBL22598549 | 0.85 | METTL3 (0.39) | — | |
| SCHEMBL26068422 | 0.85 | METTL3 (0.39) | — | |
| SCHEMBL26068482 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL22598552 | 0.78 | TYMP (0.30) | — | |
| SCHEMBL22598550 | 0.78 | TYMP (0.30) | — | |
| SCHEMBL26068428 | 0.78 | TYMP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |