Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24355440 | 0.87 | ADRB2 (0.43) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| Hydrochloric Acid SCHEMBL25368901 | 0.86 | ADRB2 (0.42) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| Hydrochloric Acid SCHEMBL25368898 | 0.86 | ADRB2 (0.42) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL18699150 | 0.82 | ADRB2 (0.45) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL14868354 | 0.82 | ADRB2 (0.42) | ADRB2NPSR1CHRNA7 | |
| SCHEMBL24908146 | 0.82 | ADRB2 (0.45) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL2609298 | 0.80 | ADRB2 (0.54) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL30176825 | 0.78 | ADRB2 (0.41) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL12775817 | 0.78 | ADRB2 (0.41) | ADRB2NPSR1NOS3NOS2KCNN4 | |
| SCHEMBL25368834 | 0.78 | ADRB2 (0.39) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234548-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Suzhou Zelgen Biopharmaceutical Co., Ltd. (CN) | 2023-08-30 | — | — | EP | disclosed |