Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115531 | 1.00 | EPHX1 (0.50) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3686292 | 1.00 | EPHX1 (0.50) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL13964480 | 1.00 | EPHX1 (0.50) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL23348055 | 1.00 | EPHX1 (0.50) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL3140310 | 1.00 | EPHX1 (0.50) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL17821994 | 0.97 | EPHX1 (0.48) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL31269777 | 0.97 | EPHX1 (0.48) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL1356285 | 0.97 | EPHX1 (0.48) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| Ammonia Solution, Strong SCHEMBL1787850 | 0.97 | EPHX1 (0.48) | EPHX1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL193153 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1017 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4107198-B1 | POLYISOCYANATE PREPARATIONS | COVESTRO DEUTSCHLAND AG (DE) | 2024-03-13 | — | — | EP | claimed |
| CN-117624415-A | Olefin polymerization system, method and anti-sticking agent used in same | 中国石油天然气股份有限公司 | 2024-03-01 | — | — | CN | claimed |
| EP-3560975-B2 | IONICALLY HYDROPHILIZED POLYISOCYANATES AND ANTIOXIDANTS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-12-06 | — | — | EP | claimed |
| EP-3724251-B2 | IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-11-22 | — | — | EP | claimed |
| EP-3851472-B1 | IONICALLY HYDROPHILIZED POLYISOCYANATES, WATER CONTENT | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-06-07 | — | — | EP | claimed |
| EP-4107198-A1 | POLYISOCYANATE PREPARATIONS | Covestro Deutschland AG (DE) | 2022-12-28 | — | — | EP | claimed |
| EP-3824009-B1 | IONICALLY HYDROPHILIZED POLYISOCYANATES WITH IMPROVED DRYING | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-03-09 | — | — | EP | claimed |
| CN-113993511-A | Methods and formulations for treating visual disorders | 杰尼视界公司 | 2022-01-28 | — | — | CN | claimed |
| CN-110407708-A | Chiral tetraphenyl ethylene tetramine for chiral carboxylic acids enantiomer identification and purity analysis | UNIV HUAZHONG SCIENCE TECH | 2019-11-05 | — | — | CN | claimed |
| CN-110294830-A | A kind of self-crosslinkable polyurethane-polyurea water dispersion and its preparation method and application | 万华化学（广东）有限公司 | 2019-10-01 | — | — | CN | claimed |
| US-20070082956-A1 | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity. | MERZ PHARMA GMBH & CO. KGAA (DE) | 2007-04-12 | — | — | US | claimed |
| EP-1682109-A1 | THE USE OF 1-AMINOCYCLOHEXANE DERIVATIVES TO MODIFY DEPOSITION OF FIBRILLOGENIC AS PEPTIDES IN AMYLOIDOPATHIES | Merz Pharma GmbH & Co. KGaA (DE) | 2006-07-26 | — | — | EP | claimed |
| WO-2006069294-A1 | 1-AMINOCYCLOHEXANE-DERIVATIVES FOR THE TREATMENT OF MULTIPLE SCLEROSIS EMOTIONAL LABILITY AND PSEUDOBULBAR AFFECT | MERZ PHARMA GMBH & CO. KGAA (DE) | 2006-06-29 | — | — | WO | claimed |
| EP-1660058-A2 | THE USE OF 1-AMINO-ALKYLCYCLOHEXANE COMPOUNDS IN THE TREATMENT OF PAIN HYPERSENSITIVITY | Merz Pharma GmbH & Co. KGaA (DE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005079779-A1 | THE USE OF 1-AMINOCYCLOHEXANE DERIVATIVES TO MODIFY DEPOSITION OF FIBRILLOGENIC Aß PEPTIDES IN AMYLOIDOPATHIES | MERZ PHARMA GMBH & CO. KGAA (DE) | 2005-09-01 | — | — | WO | claimed |
| WO-2005009421-A2 | THE USE OF 1-AMINO-ALKYLCYCLOHEXANE COMPOUNDS IN THE TREATMENT OF PAIN HYPERSENSITIVITY | MERZ PHARMA GMBH & CO. KGAA (DE) | 2005-02-03 | — | — | WO | claimed |
| EP-0973885-B1 | DISASSOCIATION OF INTERACTING MOLECULES | AFFYMETRIX INC (US) | 2004-11-03 | — | — | EP | claimed |
| US-20040087658-A1 | Synergistic mixture; Alzheimer's disease therapy | MERZ PHARMA GMBH & CO. KGAA (DE) | 2004-05-06 | — | — | US | claimed |
| EP-0058505-B1 | PREPARATION OF ESTERS CONTAINING AN ALPHA-CYANO GROUP IN THE ALCOHOL PORTION OF THE ESTERS | FMC Corporation (US) | 1985-05-29 | — | — | EP | claimed |
| US-4423263-A | REACTION WITH N-HALOGENAMINE IN PRESENCE OF PROTON DONOR AND METAL CATALYSTS | ANIC, S.P.A. (IT) | 1983-12-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082956-A1 | The use of 1-amino-alkylcyclohexane compounds in the treatment of pain hypersensitivity. | GRIN1, OPRL1, GRIN3A | EPHX1 336/4885KDM4E 1877/4885ALDH1A1 1834/4885 |
| US-20040087658-A1 | Synergistic mixture; Alzheimer's disease therapy | ACHE, BACE1, CHRNA5 | EPHX1 137/4885KDM4E 3278/4885ALDH1A1 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.