Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24355263 | 0.85 | POLB (0.46) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL24355109 | 0.82 | KRAS (0.46) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL24355416 | 0.81 | KRAS (0.59) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL3265628 | 0.80 | POLB (0.61) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL24355241 | 0.80 | POLB (0.42) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL29756065 | 0.77 | PDPK1 (0.57) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL24355432 | 0.77 | PDPK1 (0.57) | POLBLMNAGLAGAASMARCA2 | |
| SCHEMBL28941828 | 0.74 | SOS1 (0.78) | KRASSOS1 | |
| SCHEMBL24355284 | 0.74 | SOS1 (0.78) | KRASSOS1 | |
| SCHEMBL24355108 | 0.74 | PDE4A (0.45) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234548-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Suzhou Zelgen Biopharmaceutical Co., Ltd. (CN) | 2023-08-30 | — | — | EP | disclosed |