Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21945067 | 0.85 | APP (0.48) | MAOBAPPGRIN2BMRGPRX4 | |
| SCHEMBL18002223 | 0.81 | MAOB (0.56) | MAOBMRGPRX4 | |
| SCHEMBL16214988 | 0.78 | GRIN2B (0.44) | GRIN2BMRGPRX4 | |
| SCHEMBL791896 | 0.77 | MAOB (0.70) | MAOBAPPMRGPRX4 | |
| SCHEMBL17071826 | 0.76 | ALDH1A1 (0.46) | GRIN2B | |
| SCHEMBL791305 | 0.75 | MAOB (0.73) | MAOBAPPMRGPRX4 | |
| SCHEMBL1526052 | 0.74 | NPC1 (0.53) | MAOBGRIN2B | |
| SCHEMBL8198914 | 0.73 | GRIN2B (0.44) | GRIN2B | |
| SCHEMBL13463063 | 0.73 | MAOB (0.58) | MAOBMRGPRX4BCHE | |
| SCHEMBL28422875 | 0.72 | MAOB (0.62) | MAOBMRGPRX4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |