Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006158 | 0.88 | AR (0.40) | LMNANPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL18004110 | 0.84 | USP8 (0.38) | LMNANPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL18006025 | 0.84 | HTR7 (0.40) | LMNANPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL730 | 0.81 | ERBB2 (0.39) | NPC1RAB9ASMN1; SMN2LRRK2TSHR | |
| SCHEMBL18005941 | 0.81 | USP8 (0.39) | LMNATSHRNPSR1RXFP1USP8 | |
| SCHEMBL18005942 | 0.81 | HSP90AB1 (0.39) | LMNANPC1CASP3SENP7GAA | |
| SCHEMBL18005937 | 0.81 | HSP90AB1 (0.50) | LMNAGAAALDH1A1HPGDUSP8 | |
| SCHEMBL18005934 | 0.80 | NPC1 (0.42) | LMNANPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL16399347 | 0.80 | ADORA1 (0.42) | DCUN1D1HTR7ALDH1A1HPGDCYP11B1 | |
| SCHEMBL18003907 | 0.80 | DCUN1D2 (0.38) | LMNADCUN1D1LRRK2ALDH1A1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |