Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006433 | 0.85 | CYP11B1 (0.38) | IGF1RSLC22A12KDM4EMAPTEGFR | |
| SCHEMBL26071010 | 0.79 | CYP11B1 (0.38) | IGF1RSLC22A12PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26070969 | 0.76 | TAAR1 (0.43) | IGF1RKDM4EPIK3CDPIK3CAPIK3CB | |
| SCHEMBL26071092 | 0.76 | IGF1R (0.39) | IGF1RNOTUMSLC22A12KDM4EPIK3CD | |
| SCHEMBL26071045 | 0.76 | MRGPRX4 (0.45) | IGF1RKDM4EPIK3CDPIK3CAPIK3CB | |
| SCHEMBL26070963 | 0.76 | EGFR (0.43) | KDM4EPIK3CAEGFRCYP11B1CYP11B2 | |
| SCHEMBL26071016 | 0.75 | SLC22A12 (0.38) | NOTUMSLC22A12KDM4ESMN1; SMN2MAPT | |
| SCHEMBL26070984 | 0.74 | IGF1R (0.42) | IGF1RKDM4EPIK3CDPIK3CAPIK3CB | |
| SCHEMBL26071075 | 0.74 | CYSLTR2 (0.36) | IGF1RNOTUMSLC22A12KDM4EPIK3CD | |
| SCHEMBL26070898 | 0.74 | BTK (0.49) | NOTUMSLC22A12KDM4EPIK3CGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |