Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18006429 | 0.84 | CYP11B1 (0.37) | CYSLTR2CYSLTR1SLC22A12MAPTGAA | |
| SCHEMBL26071043 | 0.81 | CHEK1 (0.43) | CYSLTR2CYSLTR1NOTUMSLC22A12MAPT | |
| SCHEMBL26071010 | 0.79 | CYP11B1 (0.38) | CYSLTR2CYSLTR1SLC22A12PIK3CDPIK3CA | |
| SCHEMBL26071083 | 0.77 | SLC22A12 (0.38) | KDM4ENOTUMSLC22A12MAPTGAA | |
| SCHEMBL26071016 | 0.77 | SLC22A12 (0.38) | CYSLTR2CYSLTR1KDM4ENOTUMSLC22A12 | |
| SCHEMBL26071059 | 0.77 | PFKFB3 (0.39) | CYSLTR2CYSLTR1NOTUMSLC22A12PIK3CD | |
| SCHEMBL26071012 | 0.77 | HSD17B10 (0.38) | CYSLTR2CYSLTR1KDM4ENOTUMSLC22A12 | |
| SCHEMBL26071014 | 0.76 | FFAR1 (0.38) | CYSLTR2CYSLTR1KDM4ENOTUMSLC22A12 | |
| SCHEMBL26071079 | 0.74 | IGF1R (0.35) | CYSLTR2CYSLTR1KDM4ENOTUMSLC22A12 | |
| SCHEMBL26070984 | 0.74 | IGF1R (0.42) | KDM4EDYRK1AMAPTPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219477-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2023-08-02 | — | — | EP | disclosed |