SCHEMBL26071491

SCHEMBL26071491

CC(C)S(=O)(=O)NC1CC[CH]CC1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIA2 P42262 12/20 0.39
GRIA4 P48058 9/20 0.39
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13450369 0.84 CA12 (0.50) GRIA2GRIA4CYP1A2
SCHEMBL8223048 0.80 CA12 (0.52) GRIA2GRIA4
SCHEMBL18234121 0.80 CA12 (0.46) GRIA2GRIA4
SCHEMBL19426061 0.78 CA1 (0.56) GRIA4
SCHEMBL19426058 0.78 CA1 (0.56) GRIA4
SCHEMBL8266613 0.78 CA1 (0.56) GRIA4
SCHEMBL22455898 0.78 ALDH1A1 (0.36) GRIA2GRIA4CYP1A2
SCHEMBL1561476 0.76 CA12 (0.40)
SCHEMBL24435815 0.75 CA12 (0.41) GRIA2GRIA4CYP1A2
SCHEMBL18412745 0.75 GRIA2 (0.36) GRIA2GRIA4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717156-B EGFR inhibitor, preparation method and application thereof 南京红云生物科技有限公司 2023-05-09 CN disclosed