Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINA3 | P01011 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2607075 | 0.95 | SERPINA3 (0.49) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL2606933 | 0.90 | SERPINA3 (0.49) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL2606916 | 0.89 | SERPINA3 (0.47) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL2606973 | 0.88 | SERPINA3 (0.51) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL2606931 | 0.85 | SERPINA3 (0.50) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL13746593 | 0.84 | SERPINA3 (0.45) | SERPINA3HDAC1MGMTTMIGD3ADORA2A | |
| SCHEMBL2734833 | 0.84 | POLB (0.56) | SERPINA3HDAC1ADCY2POLBFGFR1 | |
| SCHEMBL2606986 | 0.83 | SERPINA3 (0.51) | SERPINA3HDAC1ADCY2POLBMGMT | |
| SCHEMBL14621983 | 0.82 | SERPINA3 (0.46) | SERPINA3HDAC1ADCY2POLBHPRT1 | |
| SCHEMBL2734868 | 0.82 | SERPINA3 (0.46) | SERPINA3HDAC1ADCY2POLBHPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163718-B2 | Nucleoside analogues containing phosphonate or phosphonamide groups | GILEAD SCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163718-B2 | Nucleoside analogues containing phosphonate or phosphonamide groups | GILEAD SCIENCES, INC. (US) | 2012-04-24 | — | — | US | disclosed |