Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760997 | 0.84 | CYP1A2 (0.43) | ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL2618363 | 0.82 | ALDH1A1 (0.52) | ALDH1A1CYP2C9MDM2CYP2C19LMNA | |
| SCHEMBL2602374 | 0.80 | CYP1A2 (0.52) | ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL3439911 | 0.79 | ALDH1A1 (0.49) | ALDH1A1CYP2C9HSD17B10MDM2USP2 | |
| SCHEMBL2607666 | 0.78 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL12626835 | 0.77 | GSR (0.55) | ALDH1A1CYP2C9MDM2CYP2C19LMNA | |
| SCHEMBL3439908 | 0.77 | ALDH1A1 (0.49) | ALDH1A1CYP2C9MDM2CYP2C19LMNA | |
| SCHEMBL2602436 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CYP2C9MDM2CYP2C19MAPK1 | |
| SCHEMBL2607662 | 0.76 | CYP1A2 (0.48) | ALDH1A1CYP1A2CYP3A4CYP2C9HSD17B10 | |
| SCHEMBL13998688 | 0.76 | ALDH1A1 (0.43) | ALDH1A1CYP2C9CYP2C19LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095027-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | TYMP, MKI67, CCNI | ALDH1A1 864/4885CYP1A2 1466/4885CYP3A4 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.