Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 5/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19739072 | 0.92 | CYP17A1 (0.41) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL17230049 | 0.91 | CYP17A1 (0.40) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL28458723 | 0.86 | CYP17A1 (0.42) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL19739171 | 0.86 | CYP17A1 (0.37) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL26073593 | 0.85 | CYP17A1 (0.53) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL16710976 | 0.85 | HDAC1 (0.39) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL16710975 | 0.84 | CYP17A1 (0.43) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL22824846 | 0.84 | HDAC1 (0.36) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL16710866 | 0.83 | CYP17A1 (0.42) | CYP17A1GSK3BDYRK1AMAP4K4CD274 | |
| SCHEMBL26073595 | 0.83 | CYP17A1 (0.47) | CYP17A1MAP4K4CD274PSMB8NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | PHEON THERAPEUTICS LTD (GB) | 2024-02-27 | — | — | US | disclosed |
| US-20230302142-A1 | Cytotoxic Agents | Pheon Therapeutics Ltd. (GB) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230302142-A1 | Cytotoxic Agents | ANXA11, ANXA5, HAX1 | CYP17A1 3163/4885GSK3B 233/4885DYRK1A 3726/4885 |
| US-11912700-B2 | Anti-proliferative agents comprising substituted benzo[e]pyrido[1,2-a][1,4]diazepines | MKI67, CCND2, CCND1 | CYP17A1 1348/4885GSK3B 827/4885DYRK1A 753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.