SCHEMBL26073643

SCHEMBL26073643

Cc1c(-c2cccc3sc4ccccc4c23)cccc1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.42
RARA P10276 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
BRDT Q58F21 1/20 0.36
MAPT P10636 5/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
POLB P06746 2/20 0.35
KMT2A Q03164 2/20 0.35
GAA P10253 1/20 0.35
KIF11 P52732 1/20 0.34
DUSP3 P51452 2/20 0.33
HPGD P15428 2/20 0.33
RAB9A P51151 2/20 0.33
PTPN7 P35236 1/20 0.33
PTPN12 Q05209 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21971994 0.89 GPR3 (0.47) GPR3RARARXRARXRBRXRG
Bromide SCHEMBL28718552 0.86 GPR3 (0.44) GPR3RARARXRARXRBRXRG
SCHEMBL26073646 0.85 GPR3 (0.48) GPR3BRDTMAPTALDH1A1MEN1
SCHEMBL26270551 0.85 GPR3 (0.42) GPR3RARARXRARXRBRXRG
SCHEMBL21971533 0.85 GPR3 (0.42) GPR3RARARXRARXRBRXRG
SCHEMBL2388003 0.84 GPR3 (0.56) GPR3MAPTALDH1A1MEN1POLB
SCHEMBL26073645 0.83 PARP14 (0.49) GPR3RARARXRARXRBRXRG
SCHEMBL24776019 0.81 GPR3 (0.39) GPR3BRDTMAPTALDH1A1MEN1
SCHEMBL21972208 0.81 GPR3 (0.43) GPR3BRDTMAPTALDH1A1MEN1
SCHEMBL25456488 0.81 GPR3 (0.48) GPR3MAPTALDH1A1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 GPR3 427/4885RARA 353/4885RXRA 491/4885
US-20230303602-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 GPR3 1306/4885RARA 1529/4885RXRA 1521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.