SCHEMBL2607520

SCHEMBL2607520

Cc1cc2c3c(cc(C)c4c3c1C(=O)OC4=O)C(=O)OC2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP19A1 P11511 1/20 0.37
TYMS P04818 1/20 0.35
AKR1B1 P15121 1/20 0.33
NQO1 P15559 2/20 0.33
POR P16435 2/20 0.33
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C19 P33261 2/20 0.32
TSHR P16473 2/20 0.31
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23665376 0.93 ALOX15 (0.39) ALOX15TDP1CYP19A1TYMSAKR1B1
SCHEMBL13713810 0.83 TSHR (0.34) ALOX15TDP1CYP19A1TYMSAKR1B1
SCHEMBL13010657 0.82 TDP1 (0.40) ALOX15TDP1TYMSNQO1POR
SCHEMBL12894517 0.79 CYP19A1 (0.30) CYP19A1
SCHEMBL23665496 0.77 ESR1 (0.32) KDM4ECYP1A2CYP2C19
SCHEMBL24819503 0.77
SCHEMBL14296961 0.77 TYMS (0.33) TYMSAKR1B1
SCHEMBL1298310 0.76 ALOX15 (0.48) ALOX15TDP1TYMSNQO1POR
SCHEMBL4117969 0.76 TDP1 (0.39) ALOX15TDP1CYP19A1NQO1POR
SCHEMBL30971010 0.76 TDP1 (0.39) ALOX15TDP1CYP19A1NQO1POR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120319567-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND LIGHT-EMITTING POLYMER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-12-20 US disclosed
US-20120091449-A1 ORGANIC ELECTROLUMINESCENT ELEMENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-19 US disclosed