Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.62 |
| ▸ | DHODH | Q02127 | 6/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23590240 | 0.89 | DHODH (0.73) | DHODHKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL26074163 | 0.87 | PLA2G2A (0.59) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074129 | 0.85 | PLA2G2A (0.74) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074176 | 0.84 | PLA2G2A (0.53) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074208 | 0.84 | PLA2G2A (0.56) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074173 | 0.84 | PLA2G2A (0.56) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074194 | 0.83 | PLA2G2A (0.55) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074143 | 0.83 | PLA2G2A (0.72) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL28677971 | 0.83 | PLA2G2A (0.73) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 | |
| SCHEMBL26074148 | 0.82 | PLA2G2A (0.71) | PLA2G2ADHODHKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | OHIO STATE INNOVATION FOUNDATION (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303710-A1 | METHODS AND COMPOSITIONS FOR INHIBITION OF DIHYDROOROTATE DEHYDROGENASE IN COMBINATION WITH AN ANTI-CD38 THERAPEUTIC AGENT | DHODH, CD38, DPYD | PLA2G2A 1679/4885DHODH 1/4885KDM4E 1396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.