Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.53 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226228 | 0.85 | CYP1A2 (0.58) | TMPRSS4KMT2AMEN1TSHRKDM4E | |
| SCHEMBL26074394 | 0.85 | ALDH1A1 (0.66) | PPARGNR1H4KMT2AMEN1MAPK14 | |
| SCHEMBL2951980 | 0.82 | MTOR (0.58) | TMPRSS4KMT2AMEN1TSHRMAPK14 | |
| SCHEMBL22024996 | 0.82 | GAA (0.51) | PPARGNR1H4TMPRSS4KMT2AMEN1 | |
| SCHEMBL15652931 | 0.82 | NR1H4 (0.58) | PPARGNR1H4TRPV1KMT2AMEN1 | |
| SCHEMBL22025009 | 0.81 | PTGS1 (0.54) | TMPRSS4KMT2AMEN1TSHRKDM4E | |
| SCHEMBL22065213 | 0.81 | GAA (0.53) | PPARGNR1H4TMPRSS4KMT2AMEN1 | |
| SCHEMBL2949476 | 0.80 | TMPRSS4 (0.53) | PPARGNR1H4TMPRSS4KMT2AMEN1 | |
| SCHEMBL19669082 | 0.80 | MEN1 (0.57) | TRPV1TMPRSS4KMT2AMEN1TSHR | |
| SCHEMBL18205840 | 0.80 | MEN1 (0.57) | PPARGNR1H4TRPV1TMPRSS4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | PPARG 2458/4885NR1H4 2474/4885TRPV1 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.