Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 11/20 | 0.54 |
| ▸ | PRKCB | P05771 | 9/20 | 0.54 |
| ▸ | BRD4 | O60885 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 4/20 | 0.40 |
| ▸ | PRKCG | P05129 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417672 | 0.81 | GSK3B (0.44) | DYRK1AGSK3BPRKCBBRD4PRKCA | |
| SCHEMBL7411984 | 0.77 | BRD9 (0.46) | DYRK1AGSK3BPRKCBBRD4PDE4A | |
| SCHEMBL15524666 | 0.74 | GSK3B (0.72) | DYRK1AGSK3BPRKCBCES2PRKCA | |
| SCHEMBL8692020 | 0.74 | CNR1 (0.50) | DYRK1AGSK3BPRKCBL3MBTL1 | |
| SCHEMBL8691517 | 0.74 | HSD17B10 (0.46) | GSK3BPRKCBPDE4APDE4BPDE4C | |
| SCHEMBL27748592 | 0.74 | GSK3B (0.50) | DYRK1AGSK3BPRKCBBRD4CES2 | |
| SCHEMBL24458170 | 0.74 | CFTR (0.55) | DYRK1AGSK3BPRKCBPDE4APDE4B | |
| SCHEMBL18993230 | 0.73 | DYRK1A (0.49) | DYRK1AGSK3BPRKCBCES2PDE4A | |
| SCHEMBL5251124 | 0.73 | HDAC3 (0.53) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL2546290 | 0.72 | CNR1 (0.51) | DYRK1AGSK3BPRKCBCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303584-A1 | 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF | CIT THERAPEUTICS LLC | 2023-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303584-A1 | 4,5,6,7-TETRAHYDROTHIENO[2,3-C]PYRIDINE SUMO INHIBITORS AND USES THEREOF | SUMO1, SUMO3, SUMO2 | DYRK1A 3744/4885GSK3B 3469/4885PRKCB 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.