Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | POLA1 | P09884 | 6/20 | 0.46 |
| ▸ | KARS1 | Q15046 | 3/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31291111 | 0.81 | AR (0.68) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL3212768 | 0.76 | CYP3A4 (0.78) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL20364223 | 0.76 | CYP3A4 (0.78) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL3706021 | 0.76 | CYP3A4 (0.69) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL30467251 | 0.75 | CYP3A4 (0.58) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL14207873 | 0.73 | CYP3A4 (0.74) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL14201538 | 0.73 | CYP3A4 (0.74) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL15388987 | 0.73 | CYP3A4 (0.64) | CYP3A4ALDH1A1MAPTALOX15AR | |
| SCHEMBL15388986 | 0.73 | CYP3A4 (0.64) | CYP3A4ALDH1A1MAPTALOX15AR | |
| 7-Oxocallitrisic Acid, Methyl Ester SCHEMBL15339316 | 0.72 | CYP3A4 (1.00) | CYP3A4ALDH1A1MAPTALOX15AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310531-A1 | TRIPTERYGIUM WILFORDII COMPOSITION FOR INHIBITING DRUG-RESISTANT CANCER, AND PREPARATION METHOD AND USE THEREOF | HUAQIAO UNIVERSITY (CN) | 2023-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230310531-A1 | TRIPTERYGIUM WILFORDII COMPOSITION FOR INHIBITING DRUG-RESISTANT CANCER, AND PREPARATION METHOD AND USE THEREOF | TYMS, OXER1, TOP2B | CYP3A4 121/4885ALDH1A1 396/4885MAPT 4709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.