SCHEMBL26080809

SCHEMBL26080809

O=C(O)/C(F)=C/C1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.44
GRIK2 Q13002 1/20 0.42
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
GABRR1 P24046 1/20 0.33
NPC1 O15118 3/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
HTT P42858 1/20 0.31
GAA P10253 1/20 0.31
EPHX1 P07099 4/20 0.30
RAB9A P51151 2/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13858246 0.88
SCHEMBL13858244 0.88
SCHEMBL13858145 0.88
SCHEMBL5698392 0.76 GRIK1 (0.47) GRIK1GRIK2CES2CES1NPC1
SCHEMBL5698394 0.76 GRIK1 (0.47) GRIK1GRIK2CES2CES1NPC1
SCHEMBL6474117 0.76 GRIK1 (0.47) GRIK1GRIK2CES2CES1NPC1
SCHEMBL15673252 0.76 GRIK1 (0.47) GRIK1GRIK2CES2CES1NPC1
SCHEMBL6474115 0.76 GRIK1 (0.47) GRIK1GRIK2CES2CES1NPC1
SCHEMBL15673206 0.73 GRIK1 (0.46) GRIK1GRIK2CES2CES1NPC1
SCHEMBL1582039 0.73 GRIK1 (0.44) GRIK1GRIK2CES2CES1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S GRIK1 3489/4885GRIK2 3996/4885CES2 1806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.