SCHEMBL26080824

SCHEMBL26080824

CC(C)(C)OC(=O)/C(=C\c1ccccc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
HTT P42858 1/20 0.51
TP53 P04637 1/20 0.49
AKR1C3 P42330 1/20 0.47
AKR1C1 Q04828 1/20 0.42
NR1H4 Q96RI1 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
CYP2C9 P11712 2/20 0.39
CYP3A4 P08684 1/20 0.39
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C19 P33261 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13241270 0.95 MEN1 (0.58) MEN1KMT2AHTTTP53AKR1C3
SCHEMBL3227832 0.88 MEN1 (0.51) MEN1KMT2AHTTAKR1C3LMNA
SCHEMBL3227838 0.88 MEN1 (0.51) MEN1KMT2AHTTAKR1C3LMNA
SCHEMBL8747410 0.88 KMT2A (0.51) MEN1KMT2AHTTAKR1C3NR1H4
SCHEMBL13431366 0.88 MEN1 (0.51) MEN1KMT2AHTTAKR1C3LMNA
SCHEMBL1905155 0.82 MEN1 (0.47) MEN1KMT2AHTTAKR1C3AKR1C1
SCHEMBL28915528 0.81 AKR1C3 (0.58) MEN1KMT2AHTTAKR1C3ALDH1A1
SCHEMBL20853874 0.81 AKR1C3 (0.58) MEN1KMT2AHTTAKR1C3ALDH1A1
SCHEMBL1887493 0.81 MEN1 (0.48) MEN1KMT2AHTTAKR1C3NR1H4
SCHEMBL1887498 0.81 MEN1 (0.48) MEN1KMT2AHTTAKR1C3NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2023-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230314934-A1 PHOTOACTIVE COMPOUNDS, PHOTORESIST COMPOSITIONS INCLUDING THE SAME, AND PATTERN FORMATION METHODS CRY1, CBR3, C1S MEN1 1410/4885KMT2A 2240/4885HTT 3650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.