SCHEMBL2608101

SCHEMBL2608101

Nc1ccc(N2CCC(CC3CCN(c4ccc(N)cc4)CC3)CC2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 4/20 0.53
L3MBTL1 Q9Y468 4/20 0.53
GAA P10253 3/20 0.53
HTT P42858 2/20 0.53
KMT2A Q03164 2/20 0.53
THRB P10828 2/20 0.53
RECQL P46063 2/20 0.53
MEN1 O00255 1/20 0.53
NPC1 O15118 1/20 0.53
USP2 O75604 1/20 0.53
TP53 P04637 1/20 0.53
POLB P06746 1/20 0.53
ALOX15 P16050 1/20 0.53
RAB9A P51151 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
HSD17B10 Q99714 1/20 0.53
GFER P55789 4/20 0.52
LMNA P02545 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13829265 0.91 MAPT (0.49) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL15651158 0.86 MAPT (0.52) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL1789020 0.85 MAPT (0.58) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL520612 0.85 MAPT (0.50) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL10054726 0.85 MAPT (0.50) MAPTALDH1A1KDM4EL3MBTL1GAA
Hydrochloric Acid SCHEMBL3566395 0.83 MAPT (0.53) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL25188789 0.82 MAPT (0.54) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL2448590 0.82 MAPT (0.47) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL15650569 0.82 MAPT (0.50) MAPTALDH1A1KDM4EL3MBTL1GAA
SCHEMBL17264101 0.81 MAPT (0.59) MAPTALDH1A1KDM4EL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10000702-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-06-19 US disclosed
US-9976085-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-9976088-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element having the same CHI MEI CORPORATION (TW) 2018-05-22 US disclosed
US-20180079961-A1 PHOTOALIGNMENT COMPOSITION ROLIC AG (CH) 2018-03-22 US disclosed
US-9765235-B2 Photoaligning material ROLIC AG (CH) 2017-09-19 US disclosed
US-20170184923-A1 LIQUID CRYSTAL DISPLAY ELEMENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL ALIGNMENT TREATMENT AGENT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2017-06-29 US disclosed
US-20170152443-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-06-01 US disclosed
US-9644147-B2 Liquid crystal alignment agent, liquid crystal alignment film, and liquid crystal display element CHI MEI CORPORATION (TW) 2017-05-09 US disclosed
US-20170029703-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT HAVING THE SAME CHI MEI CORPORATION (TW) 2017-02-02 US disclosed
US-20170022419-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2017-01-26 US disclosed
US-8435609-B2 Liquid crystal alignment agent, liquid crystal alignment film formed therefrom, and liquid crystal display element provided with the liquid crystal alignment film CHI MEI CORPORATION (TW) 2013-05-07 US disclosed
US-20130035446-A1 PHOTOALIGNING MATERIAL ROLIC AG (CH) 2013-02-07 US disclosed
US-20120316317-A1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION ROLIC AG (CH) 2012-12-13 US disclosed
WO-2012161329-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学工業株式会社 (JP) 2012-11-29 WO disclosed
US-20120172542-A1 Liquid Crystal (LC) Alignment Agent, LC Alignment Film And LC Display Device Having Thereof CHI MEI CORPORATION (TW) 2012-07-05 US disclosed
US-20120162588-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2012-06-28 US disclosed
US-20120101224-A1 LIQUID CRYSTAL ALIGNMENT AGENT, AND LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT FORMED FROM THE LIQUID CRYSTAL ALIGNMENT AGENT CHI MEI CORPORATION (TW) 2012-04-26 US disclosed
WO-2012005266-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学工業株式会社 (JP) 2012-01-12 WO disclosed
US-20110255042-A1 METHOD FOR MAKING A TREATED POLYMER FOR A LIQUID CRYSTAL ALIGNMENT AGENT, THE TREATED POLYMER MADE THEREBY, AND LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT CONTAINING THE TREATED POLYMER CHI MEI CORPORATION (TW) 2011-10-20 US disclosed
US-20110082237-A1 Liquid crystal alignment agent, liquid crystal alignment film formed therefrom, and liquid crystal display element provided with the liquid crystal alignment film CHI-MEI CORPORATION 2011-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316317-A1 PHOTOALIGNING MATERIAL WITH LATERAL SUBSTITUTION LATS1, LATS2, LCP1 MAPT 440/4885ALDH1A1 4503/4885KDM4E 3425/4885
US-20130035446-A1 PHOTOALIGNING MATERIAL MAP1LC3C, MAP1LC3A, LCP1 MAPT 84/4885ALDH1A1 3420/4885KDM4E 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.