MAP1LC3A

Microtubule-associated protein 1 light chain 3 alpha · Q9H492 · MAP1LC3A on Sugi Atlas →

2,782 patent compounds predicted against MAP1LC3A, 1,662 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL193131 SCHEMBL193131 0.44 10/20
SCHEMBL8489107 SCHEMBL8489107 0.49 8/20
SCHEMBL8945477 SCHEMBL8945477 0.39 7/20
SCHEMBL6276622 SCHEMBL6276622 0.57 4/20
SCHEMBL8488403 SCHEMBL8488403 0.53 4/20
SCHEMBL6277138 SCHEMBL6277138 0.53 4/20
SCHEMBL6277201 SCHEMBL6277201 0.53 4/20
SCHEMBL8488462 SCHEMBL8488462 0.53 4/20
SCHEMBL8489872 SCHEMBL8489872 0.53 4/20
SCHEMBL8490526 SCHEMBL8490526 0.50 4/20
SCHEMBL1493251 SCHEMBL1493251 0.48 4/20
SCHEMBL960281 SCHEMBL960281 0.46 4/20
SCHEMBL8765583 SCHEMBL8765583 0.58 3/20
SCHEMBL8490618 SCHEMBL8490618 0.53 3/20
SCHEMBL8446273 SCHEMBL8446273 0.52 3/20
SCHEMBL8490540 SCHEMBL8490540 0.50 3/20
SCHEMBL8492040 SCHEMBL8492040 0.50 3/20
SCHEMBL613225 SCHEMBL613225 0.46 3/20
SCHEMBL9209799 SCHEMBL9209799 0.45 3/20
SCHEMBL8945575 SCHEMBL8945575 0.39 3/20

Clinical trials — most relevant to MAP1LC3A by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation (DIAN-TU) PHASE2/PHASE3ACTIVE_NOT_RECRUITING
Efficacy of Lithium Against Chemotherapy Induced Neutropenia in Breast Cancer Patients PHASE3COMPLETED
A Multicenter Study of NAP (AL-108) in Schizophrenia PHASE2COMPLETED
LCL161 in Treating Patients With Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocytosis Myelofibrosis PHASE2COMPLETED
Clostridium Butyricum in Stenosing Crohn's Desease PHASE1/PHASE2NOT_YET_RECRUITING
FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer PHASE1/PHASE2COMPLETED
Effects of Cannabidiol (CBD) on the Activation of Autophagy and Inflammation Genes, Functional Consequences in Virologically Controlled HIV-infected Patients PHASE2COMPLETED
Effects of Lithium Therapy on Blood-based Therapeutic Targets in Parkinson's Disease. PHASE1COMPLETED
Nilotinib in Huntington's Disease PHASE1UNKNOWN
Far Infrared Irradiation for the Management, Control and Treatment of Frontotemporal Dementia PHASE1UNKNOWN
Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction EARLY_PHASE1RECRUITING
Immunohistochemical Assessment of Programmed Death ligand1 and LC3B in GBM nanUNKNOWN
Generating Intervals of Reference FFor Early Life Brain Biomarkers. nanRECRUITING
Autophagy Bladder Cancer nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Autophagy Markers in Endometrial Polyps nanCOMPLETED
Evaluation of a Novel PET Radioligand to Image OGA nanCOMPLETED
Correlation Between Autophagy-related Proteins and Inflammatory Markers in Hemodialysis Patients nanCOMPLETED
Time Course for Fasting-induced Autophagy in Humans nanWITHDRAWN
Neurofilament Light- Chain in Ataxia Telangiectasia nanUNKNOWN
Fasting, Exercise, and Diet to Activate Autophagy in Depression nanNOT_YET_RECRUITING
Muscle Insulin Resistance in Aging (Mirage) nanACTIVE_NOT_RECRUITING
Effect of Non-chirurgical Periodontal Treatment on the Immune System From a Gender Perspective nanCOMPLETED
Molecular Profile of the Evolution of Inclusion Body Myositis nanCOMPLETED
Evaluation of Serum Autophagic Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Individuals nanENROLLING_BY_INVITATION
Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial nanRECRUITING
Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging nanNOT_YET_RECRUITING
Association of Autophagy-related Genes ,LncRNA and SNPs With Colorectal Cancer in Egyptian Population nanCOMPLETED
Natural History and Disease Progression Biomarkers of Multiple System Atrophy nanCOMPLETED
Strong Evidence: Digitally Delivered Exercise in Older Adults nanACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MAP1LC3A binder may also engage these)

ProteinNameSimilarity
Q6XVN8 1.000 Q6XVN8 →
Q91VR7 1.000 Q91VR7 →
Q2HJ23 1.000 Q2HJ23 →
O41515 1.000 O41515 →
Q9CQV6 1.000 Q9CQV6 →
Q23536 1.000 Q23536 →
MAP1LC3B Microtubule-associated protein 1 light chain 3 beta 1.000 landscape →
Q2RBS4 1.000 Q2RBS4 →
Q6CMF8 1.000 Q6CMF8 →
A2XXR7 1.000 A2XXR7 →
Q9DCD6 1.000 Q9DCD6 →
Q8MK68 1.000 Q8MK68 →
A6NCE7 1.000 A6NCE7 →
Q9XEB5 1.000 Q9XEB5 →
Q9BY60 1.000 Q9BY60 →
Q5QFG1 1.000 Q5QFG1 →
GABARAP Gamma-aminobutyric acid receptor-associated protein 0.999 landscape →
Q8S926 0.999 Q8S926 →
GABARAPL1 Gamma-aminobutyric acid receptor-associated protein-like 1 0.999 landscape →
Q8S925 0.999 Q8S925 →
O94272 0.999 O94272 →
P60517 0.998 P60517 →
Q8S927 0.998 Q8S927 →
P38182 0.997 P38182 →
Q9LRP7 0.997 Q9LRP7 →
Q6Z1D5 0.997 Q6Z1D5 →
P0CO54 0.997 P0CO54 →
Q5RF21 0.997 Q5RF21 →
Q62625 0.997 Q62625 →
Q09490 0.997 Q09490 →