Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 8/20 | 0.37 |
| ▸ | FAP | Q12884 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | FURIN | P09958 | 4/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26081500 | 1.00 | C3AR1 (0.40) | C3AR1GLP1RFAPPOLBCTDSP1 | |
| SCHEMBL16870158 | 0.95 | C3AR1 (0.41) | C3AR1GLP1RFAPPOLBCTDSP1 | |
| SCHEMBL16862595 | 0.95 | C3AR1 (0.41) | C3AR1GLP1RFAPPOLBCTDSP1 | |
| SCHEMBL19303642 | 0.95 | C3AR1 (0.41) | C3AR1GLP1RFAPPOLBCTDSP1 | |
| SCHEMBL29459537 | 0.94 | C3AR1 (0.42) | C3AR1GLP1RFAPPOLBCTDSP1 | |
| SCHEMBL16925642 | 0.89 | C3AR1 (0.40) | C3AR1FAPPOLBCTDSP1FURIN | |
| SCHEMBL22134344 | 0.89 | C3AR1 (0.40) | C3AR1FAPPOLBCTDSP1FURIN | |
| SCHEMBL28051813 | 0.89 | C3AR1 (0.40) | C3AR1FAPPOLBCTDSP1FURIN | |
| SCHEMBL2801888 | 0.89 | C3AR1 (0.40) | C3AR1FAPPOLBCTDSP1FURIN | |
| SCHEMBL31294572 | 0.89 | MGLL (0.36) | C3AR1FAPFURINMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230317700-A1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | ZYMEWORKS BC INC. (CA) | 2023-10-05 | — | — | US | disclosed |
| US-20230317700-A1 | CYTOTOXIC AND ANTI-MITOTIC COMPOUNDS, AND METHODS OF USING THE SAME | ZYMEWORKS BC INC. (CA) | 2023-10-05 | — | — | US | disclosed |