Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31600744 | 0.87 | RAB9A (0.51) | GSK3BDYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL12225872 | 0.85 | GSK3B (0.48) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL30298062 | 0.81 | GSK3B (0.46) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL30107231 | 0.81 | GSK3B (0.46) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL5908666 | 0.81 | GSK3B (0.46) | GSK3BDYRK1ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16905389 | 0.81 | GSK3B (0.46) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL26125387 | 0.81 | GSK3B (0.46) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL25345910 | 0.80 | GSK3B (0.45) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL16753674 | 0.80 | GSK3B (0.45) | GSK3BDYRK1ALCKCA12CA1 | |
| SCHEMBL19200617 | 0.79 | ATR (0.49) | GSK3BDYRK1ARAB9ALCKCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3668867-B1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) FLT3 INHIBITORS | UNIV REGENSBURG (DE) | 2023-10-04 | — | — | EP | disclosed |