SCHEMBL26083181

SCHEMBL26083181

CC1(C)CC(C(=O)OCCOC(=O)C(I)c2ccccc2)C(C)(C)N1O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.40
LMNA P02545 3/20 0.39
CYP3A4 P08684 3/20 0.36
TSHR P16473 3/20 0.36
ALDH1A1 P00352 3/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLC18A2 Q05940 1/20 0.35
CHRM2 P08172 5/20 0.34
CHRM1 P11229 4/20 0.34
CHRM3 P20309 4/20 0.34
CHRNB2 P17787 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
CHRM4 P08173 2/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
MAPT P10636 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26083183 0.90 SLC18A2 (0.34) CYP2D6LMNAALDH1A1SLC18A2KMT2A
SCHEMBL26083030 0.87 CYP2D6 (0.41) CYP2D6LMNACYP3A4TSHRALDH1A1
SCHEMBL26083020 0.82 CYP2D6 (0.43) CYP2D6LMNATSHRCHRM2CHRM1
SCHEMBL26083179 0.80 SLC18A2 (0.37) SLC18A2GAA
SCHEMBL21908618 0.79 GAA (0.44) SLC18A2GAAHTT
SCHEMBL20448444 0.75 CHRM1 (0.47) CYP2D6LMNACYP3A4ALDH1A1SMN1; SMN2
Bromide SCHEMBL31237442 0.74 TRAP1 (0.36) SLC18A2CHRM2CHRM1CHRM3CHRM4
SCHEMBL21908629 0.74 GAA (0.41) SLC18A2GAA
SCHEMBL21908632 0.74 GAA (0.41) SLC18A2GAA
SCHEMBL21908619 0.74 GAA (0.41) SLC18A2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11782343-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-10-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11782343-B2 Resist composition and patterning process HNRNPU, CBR1, CBR3 CYP2D6 1322/4885LMNA 2948/4885CYP3A4 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.