Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110309 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL31466742 | 1.00 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26108086 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26108825 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26083644 | 0.91 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26110277 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL31466779 | 0.90 | KMT2A (0.64) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26083655 | 0.90 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26110535 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1NPC1GAA | |
| SCHEMBL26083642 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192782-A2 | SMALL MOLECULE INHIBITORS OF LANOSTEROL SYNTHASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-10-05 | — | — | WO | disclosed |