Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 5/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26084673 | 0.95 | GABRG2 (0.37) | GABRG2GABRB3GABRA5MTNR1AMTNR1B | |
| SCHEMBL26083989 | 0.89 | GABRG2 (0.35) | GABRG2GABRB3GABRA5 | |
| SCHEMBL26083962 | 0.89 | GABRG2 (0.37) | GABRG2GABRB3GABRA5MTNR1AMTNR1B | |
| SCHEMBL26084236 | 0.87 | GABRG2 (0.36) | GABRG2GABRB3GABRA5MTNR1AMTNR1B | |
| SCHEMBL26084667 | 0.85 | GABRG2 (0.36) | GABRG2GABRB3GABRA5GPR119 | |
| SCHEMBL26084671 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA5 | |
| SCHEMBL26084729 | 0.83 | GABRG2 (0.34) | GABRG2GABRB3GABRA5MTNR1AMTNR1B | |
| SCHEMBL26084719 | 0.82 | GABRG2 (0.36) | GABRG2GABRB3GABRA5 | |
| SCHEMBL26083986 | 0.82 | GABRG2 (0.35) | GABRG2GABRB3GABRA5 | |
| SCHEMBL26084028 | 0.81 | GABRG2 (0.37) | GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192686-A1 | METHODS FOR PREVENTING OR SLOWING THE PROGRESSION OF COGNITIVE DECLINE OR IMPAIRMENT IN SUBJECTS DISPLAYING NORMAL COGNITIVE PERFORMANCE | Li shi jiang (US) | 2023-10-05 | — | — | WO | disclosed |