Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29730037 | 1.00 | RIPK1 (0.49) | RIPK1PDE5AKDM4EALDH1A1SCD5 | |
| SCHEMBL26087676 | 1.00 | RIPK1 (0.49) | RIPK1PDE5AKDM4EALDH1A1SCD5 | |
| SCHEMBL22444793 | 1.00 | RIPK1 (0.49) | RIPK1PDE5AKDM4EALDH1A1SCD5 | |
| SCHEMBL27169375 | 0.87 | RIPK1 (0.40) | RIPK1KDM4EALDH1A1SCD5DRD4 | |
| SCHEMBL27040854 | 0.87 | RIPK1 (0.40) | RIPK1KDM4EALDH1A1SCD5DRD4 | |
| SCHEMBL25202993 | 0.85 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL28459091 | 0.85 | RIPK1 (0.50) | RIPK1KDM4EALDH1A1 | |
| SCHEMBL20580700 | 0.84 | RIPK1 (0.64) | RIPK1PDE5AKDM4EALDH1A1PKM | |
| SCHEMBL18921372 | 0.84 | RIPK1 (0.64) | RIPK1PDE5AKDM4EALDH1A1PKM | |
| SCHEMBL22210923 | 0.84 | RIPK1 (0.64) | RIPK1PDE5AKDM4EALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068881-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | 주식회사 보로노이바이오 | 2023-04-27 | — | — | WO | disclosed |