Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 7/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 4/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18921305 | 0.86 | RIPK1 (0.43) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL22232765 | 0.86 | RIPK1 (0.43) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL31029872 | 0.84 | NR3C2 (0.39) | RIPK1MAOAMAOB | |
| SCHEMBL22210929 | 0.83 | POLB (0.45) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL20580089 | 0.82 | RIPK1 (0.48) | RIPK1 | |
| SCHEMBL18921354 | 0.81 | RIPK1 (0.39) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL20580690 | 0.80 | RIPK1 (0.50) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL20580294 | 0.80 | RIPK1 (0.58) | RIPK1 | |
| SCHEMBL22210961 | 0.80 | RIPK1 (0.40) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL22210915 | 0.80 | RIPK1 (0.40) | RIPK1CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250019373-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | VORONOI INC. (KR) | 2025-01-16 | — | — | US | claimed |
| CN-118475578-A | Aryl or heteroaryl derivatives for preventing or treating kinase-related diseases and pharmaceutical compositions containing the same as active ingredient | 沃若诺伊公司 | 2024-08-09 | — | — | CN | claimed |
| US-20250019373-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | VORONOI INC. (KR) | 2025-01-16 | — | — | US | disclosed |
| EP-4421077-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | Voronoi Inc. (KR) | 2024-08-28 | — | — | EP | disclosed |
| CN-118475578-A | Aryl or heteroaryl derivatives for preventing or treating kinase-related diseases and pharmaceutical compositions containing the same as active ingredient | 沃若诺伊公司 | 2024-08-09 | — | — | CN | disclosed |
| WO-2023068881-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | 주식회사 보로노이바이오 | 2023-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250019373-A1 | ARYL OR HETEROARYL DERIVATIVE, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF KINASE-RELATED DISEASES | RIPK1, RIPK2, RIPK3 | RIPK1 1/4885CHRNB2 4278/4885CHRNB4 4639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.