Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EHMT2 | Q96KQ7 | 7/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23454666 | 1.00 | MEN1 (0.58) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL31092596 | 0.87 | SIRT2 (0.57) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL23454659 | 0.87 | EHMT2 (0.54) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL27200292 | 0.86 | HDAC3 (0.47) | EHMT2MMP1MMP3MMP9SIRT2 | |
| SCHEMBL27200294 | 0.86 | HDAC3 (0.47) | EHMT2MMP1MMP3MMP9SIRT2 | |
| Hydrochloric Acid SCHEMBL27138542 | 0.85 | MEN1 (0.58) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL27138541 | 0.85 | MEN1 (0.58) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL830075 | 0.83 | EHMT2 (0.52) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL23454631 | 0.83 | HDAC4 (0.65) | MEN1ALDH1A1MAPTMAPK1KMT2A | |
| SCHEMBL26436622 | 0.83 | HDAC4 (0.65) | MEN1ALDH1A1MAPTMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | MEN1 1264/4885ALDH1A1 393/4885MAPT 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.