Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 7/20 | 0.61 |
| ▸ | CTSS | P25774 | 1/20 | 0.60 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23454631 | 1.00 | HDAC4 (0.65) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL3763472 | 0.92 | HDAC4 (0.61) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL30861281 | 0.90 | HDAC4 (0.65) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL2925561 | 0.89 | HDAC4 (0.64) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL23483309 | 0.88 | CTSK (0.55) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL27613652 | 0.87 | HDAC4 (0.61) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL31092596 | 0.87 | SIRT2 (0.57) | CTSSSIRT2SIRT1SIRT3MEN1 | |
| SCHEMBL23188882 | 0.87 | HDAC8 (0.59) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL8699255 | 0.87 | HDAC8 (0.59) | HDAC4HDAC1HDAC8HDAC3HDAC7 | |
| SCHEMBL8699259 | 0.87 | HDAC8 (0.59) | HDAC4HDAC1HDAC8HDAC3HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| EP-4066896-A1 | G9A INHIBITOR | RIKEN (JP) | 2022-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | HDAC4 237/4885HDAC1 38/4885HDAC8 201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.