Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | WNT1 | P04628 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | EZH2 | Q15910 | 6/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213563 | 0.89 | CCNC (0.38) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL26086965 | 0.78 | PDE10A (0.40) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL23240205 | 0.77 | POLB (0.41) | CCNCCDK8JAK2JAK1WNT3A | |
| SCHEMBL26087588 | 0.76 | PDE10A (0.37) | WNT1GSK3BDYRK1APDE10A | |
| SCHEMBL26739655 | 0.74 | PDE10A (0.40) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL26739721 | 0.72 | MAP3K12 (0.35) | PDE10A | |
| SCHEMBL23239922 | 0.71 | PDE10A (0.42) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL13162684 | 0.70 | CCNC (0.41) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL23213534 | 0.70 | PDE10A (0.36) | WNT1GSK3BDYRK1ACCNCCDK8 | |
| SCHEMBL23213610 | 0.69 | CNR2 (0.71) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |