Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3115448 | 0.75 | XDH (0.38) | KDM4EHSD17B10ALDH1A1NOTUMHPGD | |
| SCHEMBL6645692 | 0.72 | MEN1 (0.38) | KDM4EHSD17B10ALDH1A1GAAMEN1 | |
| SCHEMBL25381638 | 0.72 | KDM4E (0.40) | KDM4EHSD17B10SMN1; SMN2ALDH1A1NOTUM | |
| SCHEMBL11520043 | 0.70 | KDM4E (0.44) | KDM4EHSD17B10L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL26089714 | 0.69 | AURKA (0.43) | KDM4EHSD17B10L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL28863755 | 0.69 | LCK (0.44) | KDM4EHSD17B10L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL14645847 | 0.69 | KDM4E (0.46) | KDM4EHSD17B10L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL26087614 | 0.69 | NOTUM (0.46) | KDM4EHSD17B10L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL31454973 | 0.69 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL27994109 | 0.69 | KDM4E (0.48) | KDM4EHSD17B10ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |