SCHEMBL26090944

SCHEMBL26090944

CCOP(=O)(OCC)c1cccc(CN2CCNCCNCC2)n1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 7/20 0.53
HIF1A Q16665 2/20 0.36
SIGMAR1 Q99720 1/20 0.36
PRMT5 O14744 1/20 0.36
KDM5C P41229 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
LMNA P02545 1/20 0.35
CSF1R P07333 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CHRM3 P20309 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24384232 0.87 CXCR4 (0.49) CXCR4HIF1ASIGMAR1PRMT5KDM5C
SCHEMBL26885910 0.84 CXCR4 (0.46) CXCR4HIF1ASIGMAR1PRMT5KDM5C
SCHEMBL24384235 0.77 CXCR4 (0.40) CXCR4HIF1APRMT5CSF1RKDM4E
SCHEMBL26089776 0.77 KDM4E (0.38) CXCR4LMNAKDM4EALDH1A1CHRM3
SCHEMBL16093362 0.74 CXCR4 (0.69) CXCR4SIGMAR1PRMT5KDM5CKDM4C
SCHEMBL1089502 0.74 CXCR4 (0.65) CXCR4SIGMAR1KDM5CKDM4CLMNA
SCHEMBL17996820 0.74 CXCR4 (0.65) CXCR4SIGMAR1KDM5CKDM4CLMNA
Bromide SCHEMBL29604778 0.73 CXCR4 (0.78) CXCR4SIGMAR1KDM5CKDM4CLMNA
Hydrochloric Acid SCHEMBL5570623 0.73 CXCR4 (0.78) CXCR4SIGMAR1KDM5CKDM4CLMNA
Hydrochloric Acid SCHEMBL29604268 0.73 CXCR4 (0.78) CXCR4SIGMAR1KDM5CKDM4CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250222143-A1 TARGETED RADIOTHERANOSTICS BASED ON POLYAZAMACROCYCLIC, MIXED-DONOR SCAFFOLDS LINKED TO A TARGETING VECTOR THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2025-07-10 US disclosed
WO-2023070004-A1 TARGETED RADIOTHERANOSTICS BASED ON POLYAZAMACROCYCLIC, MIXED-DONOR SCAFFOLDS LINKED TO A TARGETING VECTOR THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-04-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250222143-A1 TARGETED RADIOTHERANOSTICS BASED ON POLYAZAMACROCYCLIC, MIXED-DONOR SCAFFOLDS LINKED TO A TARGETING VECTOR PAICS, RABGGTB, PARP1 CXCR4 7/4885HIF1A 2288/4885SIGMAR1 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.