⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497812 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28060128 | 0.71 | — | — | |
| SCHEMBL26500108 | 0.71 | — | — | |
| SCHEMBL16419932 | 0.71 | — | — | |
| SCHEMBL16393245 | 0.71 | — | — | |
| SCHEMBL25190471 | 0.71 | APLNR (0.32) | — | |
| Hydrochloric Acid SCHEMBL16412324 | 0.69 | MAOB (0.30) | — | |
| SCHEMBL17048665 | 0.67 | — | — | |
| SCHEMBL17812414 | 0.65 | APLNR (0.33) | — | |
| SCHEMBL22270955 | 0.65 | IDH1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069720-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |