Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30378975 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL30379559 | 0.90 | GAA (0.47) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL26091768 | 0.90 | GAA (0.47) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL30910090 | 0.88 | GAA (0.46) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL26088892 | 0.88 | GAA (0.46) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL30379553 | 0.86 | BRD4 (0.61) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL26089130 | 0.86 | BRD4 (0.61) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL26089031 | 0.85 | SIGMAR1 (0.46) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL30378990 | 0.85 | SIGMAR1 (0.46) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 | |
| SCHEMBL30379209 | 0.83 | DRD4 (0.64) | SMN1; SMN2DRD4LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | claimed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | claimed |
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | disclosed |