Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30910069 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBPKMUSP2 | |
| SCHEMBL26090516 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL30379814 | 0.88 | ALDH1A1 (0.45) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL26088422 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBALOX15MAPTDRD4 | |
| SCHEMBL30910089 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBALOX15MAPTDRD4 | |
| SCHEMBL26089229 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL30379221 | 0.85 | ALDH1A1 (0.43) | ALDH1A1KDM4EPOLBPKMMAPT | |
| SCHEMBL30910045 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBPKMUSP2 | |
| SCHEMBL26091906 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KDM4EPOLBPKMUSP2 | |
| SCHEMBL30910082 | 0.81 | ALDH1A1 (0.52) | ALDH1A1KDM4EPOLBPKMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | claimed |
| CN-118119612-A | Novel compounds and pharmaceutical compositions comprising the same | 萨皮恩斯生物有限公司 | 2024-05-31 | — | — | CN | disclosed |
| WO-2023068755-A1 | NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 사피엔스바이오 | 2023-04-27 | — | — | WO | disclosed |