Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.47 |
| ▸ | CTSL | P07711 | 16/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701451 | 0.88 | CTSS (0.61) | CTSSCTSLCTSKCTSB | |
| SCHEMBL696153 | 0.84 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL696411 | 0.84 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL696432 | 0.83 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL695203 | 0.83 | CTSS (0.60) | CTSSCTSLCTSK | |
| SCHEMBL15338583 | 0.81 | CTSS (0.39) | CTSSCTSLCTSKCTSB | |
| SCHEMBL15327207 | 0.80 | CTSS (0.53) | CTSSCTSLCTSKCTSB | |
| SCHEMBL2106860 | 0.78 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL694369 | 0.78 | CTSS (0.58) | CTSSCTSLCTSKCTSB | |
| SCHEMBL2609235 | 0.77 | CTSS (0.42) | CTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163793-B2 | Proline derivatives | HOFFMAN-LA ROCHE INC. (US) | 2012-04-24 | — | — | US | disclosed |