⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26094421 | 0.96 | — | — | |
| SCHEMBL26090922 | 0.89 | HDAC1 (0.30) | — | |
| SCHEMBL26094545 | 0.88 | — | — | |
| SCHEMBL26092014 | 0.86 | — | — | |
| SCHEMBL26094422 | 0.86 | MAP4K1 (0.33) | — | |
| SCHEMBL26133341 | 0.85 | PARP1 (0.31) | — | |
| SCHEMBL26133128 | 0.85 | MAPK1 (0.33) | — | |
| SCHEMBL26094893 | 0.85 | — | — | |
| SCHEMBL26094320 | 0.84 | PARP1 (0.31) | — | |
| SCHEMBL26094622 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |