Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26132546 | 0.96 | MAPK1 (0.33) | MAPK1 | |
| SCHEMBL26133203 | 0.89 | MAPK1 (0.36) | MAPK1 | |
| SCHEMBL26094954 | 0.88 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL26094873 | 0.86 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL26094171 | 0.85 | — | — | |
| SCHEMBL26132556 | 0.85 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL26133154 | 0.84 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL26133803 | 0.84 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL26091088 | 0.83 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL26133268 | 0.82 | MAPK1 (0.33) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066350-A1 | CRBN E3 LIGASE LIGAND COMPOUND, PROTEIN DEGRADING AGENT DEVELOPED ON THE BASIS OF LIGAND COMPOUND, AND THEIR APPLICATIONS | 标新生物医药科技(上海)有限公司 | 2023-04-27 | — | — | WO | claimed |