SCHEMBL26095006

SCHEMBL26095006

CC=CC(=O)OCCCC[SiH2]C(I)I

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 4/20 0.40
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HPGD P15428 1/20 0.33
APP P05067 4/20 0.31
GSTP1 P09211 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26091409 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26092218 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26094516 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26091329 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26096332 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26095609 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26096250 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26092782 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26094015 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4
SCHEMBL26095598 0.98 HCAR2 (0.41) ATMHCAR2TSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR ATM 934/4885HCAR2 339/4885TSHR 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.