SCHEMBL26095997

SCHEMBL26095997

CC=CC(=O)OCCCCCCCCCCCCCCCCCC[Si](C)(C)Br

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.44
ATM Q13315 1/20 0.43
TSHR P16473 2/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
APP P05067 6/20 0.34
PRKCA P17252 2/20 0.34
HPGD P15428 1/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26094185 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26091535 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095893 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095943 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095310 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26094935 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095195 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26094905 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26095328 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4
SCHEMBL26092883 1.00 HCAR2 (0.44) HCAR2ATMTSHRALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-04 US disclosed
EP-4174076-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS Shin-Etsu Chemical Co., Ltd. (JP) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134471-A1 METHOD FOR PRODUCING (METH)ACRYLOXY GROUP-CONTAINING ORGANOSILICON COMPOUNDS HM13, RPS13, GRHPR HCAR2 339/4885ATM 934/4885TSHR 765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.