SCHEMBL26096031

SCHEMBL26096031

COc1cccc(-c2cc(-c3ccc4c(c3)OCO4)n[nH]2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.69
MAPT P10636 9/20 0.57
NPC1 O15118 5/20 0.57
RAB9A P51151 5/20 0.57
NFKB1 P19838 3/20 0.57
NFKB2 Q00653 3/20 0.57
RELA Q04206 3/20 0.57
PTGS2 P35354 1/20 0.51
MAPK1 P28482 2/20 0.50
MEN1 O00255 6/20 0.47
KMT2A Q03164 6/20 0.47
HPGD P15428 3/20 0.47
USP2 O75604 2/20 0.47
TP53 P04637 2/20 0.47
ALOX15 P16050 2/20 0.47
ALOX12 P18054 2/20 0.47
HSP90AA1 P07900 1/20 0.47
TSHR P16473 1/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17279918 0.87 SNCA (0.82) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL1608353 0.84 MAPT (0.63) MAPTNPC1RAB9ANFKB1NFKB2
SCHEMBL10057827 0.84 SNCA (0.77) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL16500510 0.84 SNCA (0.73) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL7995876 0.83 SNCA (0.62) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL17279905 0.83 MAPT (0.61) MAPTNPC1RAB9ANFKB1NFKB2
SCHEMBL15425097 0.82 SNCA (0.74) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL21440053 0.81 SNCA (0.73) SNCAMAPTNPC1RAB9ANFKB1
Emrusolmin SCHEMBL21440048 0.81 SNCA (1.00) SNCAMAPTNPC1RAB9ANFKB1
SCHEMBL22890840 0.81 SNCA (0.73) SNCAMAPTNPC1RAB9ANFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US claimed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP claimed
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-07-17 US disclosed
WO-2023073115-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-04 WO disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed
EP-4173485-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-05-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250228242-A1 PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL APP, APBA1, PRNP SNCA 63/4885MAPT 8/4885NPC1 2456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.