⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260940 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL12757692 | 0.80 | ALDH1A1 (0.37) | — | |
| SCHEMBL260941 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL140703 | 0.78 | — | — | |
| SCHEMBL12757693 | 0.77 | ALDH1A1 (0.34) | — | |
| SCHEMBL2612027 | 0.76 | ALDH1A1 (0.65) | — | |
| SCHEMBL4984202 | 0.74 | — | — | |
| SCHEMBL270159 | 0.74 | — | — | |
| SCHEMBL7540967 | 0.74 | — | — | |
| SCHEMBL29042287 | 0.73 | TDP1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436063-B2 | Polymer polyols and polymer dispersions made from vegetable oil-based hydroxyl-containing materials | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8318829-B2 | Methylene bis(cyclohexylamine)-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318828-B2 | 1,3- or 1,4-bis(aminomethyl)cyclohexane-initiated polyols and rigid polyurethane foam made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-20120172470-A1 | POLYOL MIXTURES CONTAINING A 1,3- AND/OR 1,4-BIS(AMINOMETHYL)CYCLOHEXANE-INITIATED POLYOL AND AT LEAST ONE OF A METHYLENE BIS(CYCLOHEXYLAMINE)-INITIATED POLYOL AND A CYCLOHEXANEDIAMINE-INITIATED POLYOL, AND POLYURETHANES MADE THEREFROM | MORLEY TIMOTHY A (CH) | 2012-07-05 | — | — | US | disclosed |
| US-8133930-B2 | Polyurethane foams made from hydroxymethyl-containing polyester polyols | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-03-13 | — | — | US | disclosed |
| US-20110253277-A1 | POLYURETHANE OR POLYURETHANE-UREA TIRE FILLINGS PLASTICIZED WITH FATTY ACID ESTERS | DOW DEUTSCHLAND GMBH & CO. OHG (DE) | 2011-10-20 | — | — | US | disclosed |
| US-20110130477-A1 | RIGID POLYURETHANE FOAM SYSTEMS BASED ON ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS | BIRCH ADRIAN J | 2011-06-02 | — | — | US | disclosed |
| US-20110124759-A1 | POLYOL BLENDS CONTAINING ORTHO-CYCLOHEXANEDIAMINE-INITIATED POLYOLS FOR RIGID POLYURETHANE FOAMS | BIRCH ADRIAN J | 2011-05-26 | — | — | US | disclosed |
| US-7928161-B2 | Useful in a variety of coating, sealant, adhesive, cast articles, thin-walled articles such as gloves, including medical or surgical gloves, condoms; can be blended with a variety of types of useful additives including fillers, dryers, pesticides, fertilizers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-04-19 | — | — | US | disclosed |
| US-20110077314-A1 | 1,3- OR 1,4-BIS(AMINOMETHYL)CYCLOHEXANE-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2011-03-31 | — | — | US | disclosed |
| US-20110077315-A1 | METHYLENE BIS(CYCLOHEXYLAMINE)-INITIATED POLYOLS AND RIGID POLYURETHANE FOAM MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2011-03-31 | — | — | US | disclosed |
| US-20110039968-A1 | POLYURETHANE ELASTOMERS FROM RENEWABLE RESOURCES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-17 | — | — | US | disclosed |
| US-20100280187-A1 | REACTION INJECTION MOLDED POLYURETHANES MADE USING HIGH LEVELS OF NATURAL OIL-BASED POLYOLS | GOLDHAWK MARK G | 2010-11-04 | — | — | US | disclosed |
| US-20100280140-A1 | Thermally Insulating Isocyanate-Based Foams | MORLEY TIMOTHY A | 2010-11-04 | — | — | US | disclosed |
| US-7794814-B2 | hydroxymethyl modified alkyd resin containing polyetherurethane copolymer; polyols derived from annually renewable resources; maintaining important properties like edge curl, tuftbind, viscosity and good curing rates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100010110-A1 | POLYURETHANE FOAMS MADE FROM HYDROXYMETHYL-CONTAINING POLYESTER POLYOLS AND TERTIARY AMINE-CONTAINING POLYOLS | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-01-14 | — | — | US | disclosed |
| US-20090197984-A1 | Polymer polyols and polymer dispersions made from vegetable oil-based hydroxyl-containing materials | DOW BENELUX B.V. (NL) | 2009-08-06 | — | — | US | disclosed |
| US-20090197035-A1 | hydroxymethyl modified alkyd resin containing polyetherurethane copolymer; polyols derived from annually renewable resources; maintaining important properties like edge curl, tuftbind, viscosity and good curing rates | DOW GLOBAL TECHNOLOGIES LLC | 2009-08-06 | — | — | US | disclosed |
| US-20080096995-A1 | Prepolymers Made From Hydroxymethyl-Containing Polyester Polyols Derived From Fatty Acids | DOW GLOBAL TECHNOLOGIES INC. | 2008-04-24 | — | — | US | disclosed |
| US-20080097044-A1 | Useful in a variety of coating, sealant, adhesive, cast articles, thin-walled articles such as gloves, including medical or surgical gloves, condoms; can be blended with a variety of types of useful additives including fillers, dryers, pesticides, fertilizers | DOW GLOBAL TECHNOLOGIES LLC | 2008-04-24 | — | — | US | disclosed |