Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 4/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26099908 | 0.85 | EGFR (0.54) | KITPDGFRBCSF1RHDAC3HDAC1 | |
| SCHEMBL29238233 | 0.81 | PDGFRB (0.50) | KITPDGFRBHDAC3HDAC1HDAC6 | |
| SCHEMBL26100129 | 0.79 | KIT (0.43) | KITHDAC3HDAC1HDAC6HDAC4 | |
| SCHEMBL26100134 | 0.76 | KIT (0.46) | KITPDGFRBHDAC3HDAC1HDAC6 | |
| SCHEMBL30394615 | 0.74 | KDR (0.49) | KITPDGFRBCSF1RHDAC1KDR | |
| SCHEMBL29238333 | 0.74 | KDR (0.49) | KITPDGFRBCSF1RHDAC1KDR | |
| SCHEMBL26101857 | 0.73 | KIT (0.42) | KITPDGFRBEGFRKDR | |
| SCHEMBL29238215 | 0.72 | KDR (0.54) | KITPDGFRBCSF1RFLT3HDAC1 | |
| SCHEMBL30394611 | 0.72 | KDR (0.54) | KITPDGFRBCSF1RFLT3HDAC1 | |
| SCHEMBL30394637 | 0.71 | KDR (0.55) | PDGFRBCSF1RFLT3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | claimed |
| WO-2023075529-A1 | QUINAZOLINE DERIVATIVE COMPOUND AND USE THEREOF | 보로노이바이오 주식회사 | 2023-05-04 | — | — | WO | disclosed |