Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 15/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24607783 | 1.00 | DDB1 (0.52) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL29751294 | 1.00 | DDB1 (0.52) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL26100496 | 0.96 | DDB1 (0.49) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL31160731 | 0.95 | DDB1 (0.55) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL22526682 | 0.95 | DDB1 (0.55) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL23540784 | 0.95 | DDB1 (0.55) | DDB1CRBNPDE4BKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL30258269 | 0.94 | DDB1 (0.54) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL22835695 | 0.94 | DDB1 (0.53) | DDB1CRBNPDE4B | |
| SCHEMBL31068575 | 0.92 | DDB1 (0.52) | DDB1CRBNPDE4BKDM4EMAPT | |
| SCHEMBL31323431 | 0.92 | DDB1 (0.54) | DDB1CRBNPDE4BKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250051338-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2025-02-13 | — | — | US | disclosed |
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4423086-A1 | TYK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051338-A1 | TYK2 DEGRADERS AND USES THEREOF | TYK2, DYRK2, DYRK1A | DDB1 2403/4885CRBN 111/4885PDE4B 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.