SCHEMBL31068575

SCHEMBL31068575

Cn1c(=O)n(C2CCCC(=O)NC2=O)c2ccc(C3CCN(C(=O)OC(C)(C)C)CC3)cc21

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 13/20 0.52
▸ CRBN Q96SW2 13/20 0.52
▸ KDM4E B2RXH2 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ THRB P10828 1/20 0.45
▸ PDE4B Q07343 1/20 0.42
▸ PIK3CA P42336 2/20 0.40
▸ PRKDC P78527 2/20 0.40
▸ MTOR P42345 1/20 0.40
▸ NAMPT P43490 1/20 0.40
▸ HRH3 Q9Y5N1 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23540784 0.96 DDB1 (0.55) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31160731 0.96 DDB1 (0.55) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL22526682 0.96 DDB1 (0.55) DDB1CRBNKDM4EMAPTTHRB
Hydrochloric Acid SCHEMBL30258269 0.95 DDB1 (0.54) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31323431 0.92 DDB1 (0.54) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL29751294 0.92 DDB1 (0.52) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24607783 0.92 DDB1 (0.52) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL26100192 0.92 DDB1 (0.52) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL24480442 0.91 DDB1 (0.51) DDB1CRBNKDM4EMAPTTHRB
SCHEMBL31281910 0.91 DDB1 (0.53) DDB1CRBNKDM4EMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 — — US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 — — EP disclosed
WO-2024150815-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR 田辺三菱製薬株式会社 2024-07-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL DDB1 2368/4885CRBN 1/4885KDM4E 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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