Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 11/20 | 0.55 |
| ▸ | ESRRA | P11474 | 8/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | ESRRB | O95718 | 7/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29871506 | 1.00 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23388584 | 1.00 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL29871820 | 0.99 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL29871817 | 0.99 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23388750 | 0.99 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL30489035 | 0.99 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL26099847 | 0.99 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| Hydrochloric Acid SCHEMBL32689581 | 0.99 | ESR1 (0.54) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL26462275 | 0.97 | ESR1 (0.53) | ESR1ESRRAESR2CYP3A4CYP2C19 | |
| SCHEMBL23388566 | 0.96 | ESR1 (0.55) | ESR1ESRRAESR2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137764-A1 | PRODRUGS OF FULVESTRANT | ACQUIOM AGENCY SERVICES, AS COLLATERAL AGENT | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137764-A1 | PRODRUGS OF FULVESTRANT | CYP19A1, PGR, ESR1 | ESR1 3/4885ESRRA 23/4885ESR2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.